2022.01.24 13:44 Thomassie44_ Do you guys also pack that annoying volland from your packs
2022.01.24 13:43 TeriZhu P4S | 🏰 HAPPYVILLE 🏰 | ✅ Free 24hr Trials | Automated Global CDN🌍 | 100%LocalStorage | Discord Support | HappyTV & More
2022.01.24 13:43 cinematrick Tattooed British Model Warren Phillips
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2022.01.24 13:43 planthouseandgarden Happy Monstera Monday 🍃
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2022.01.24 13:43 the_deathmaster77 Steakhouse
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2022.01.24 13:43 EngineerNeedles Is there an ETA on Fishing Apptitude Fix?
I'm currently playing on the Kshira Sagara server on US West. And I'm Currently 30th Apptitude in Fishing but I've never received my 3rd Apptitude box per level (I've received the 1/3 and the 2/3). And I started on that server on Christmas Eve. And no, I'm not a bot lol. I do stream my fishing (boring I know) I'm also doing a personal challenge that requires fishing. (Info on that challenge is on my platform about page).
Now that that's cleared up, has anyone heard about a fix anytime soon?
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2022.01.24 13:43 niely9600 OPI abstract after dark. Haven't been able to have my nails done in a while. This was a fun color to find. Purple with some glitter effect
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2022.01.24 13:43 AwesomeToodles Pls tell me you'll let me go with you next time 🥺
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2022.01.24 13:43 HovercraftWonderful7 Regice be online 9506 2533 1349 and 3832 5554 5370
2022.01.24 13:43 DiogenesK-9 The Case for Impeaching Clarence Thomas — The Supreme Court justice refuses to recuse himself from cases in which his right-wing activist wife, Ginni, has a clear interest. Ginni got more than $200,000 from one person who had a brief in front of the court, and only the Thomases knew about it...
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2022.01.24 13:43 Skuntpunch_ A great investment to stop sin
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2022.01.24 13:43 Darkshade_10 Do my earrings have powers?
This Is a weird question but I need help. I wear the same earrings everyday not because I want to necessarily but because I feel like if I don't bad things will happen. There have been a number of times where when I didn't wear a particular pair of earrings bad things would happen to me nothing big but small things though. Do my earrings have some kind of power or something so I have to wear them? Why can't I wear any other pair. This is really weird and I need to know what's going on.
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2022.01.24 13:43 LycanNord123 21m Ireland, looking for cool, amazing and nerdy friends !
How is everyone?? I hope you are all doing well!!! And I hope that you are enjoying your day !
So I am here today to meet and make some new friends with who I can have fun with
So here a list of stuff about me
2022.01.24 13:43 Jova38 Tried my hand with a Pokémon Themed Mr. Incredible Meme with Original Music
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2022.01.24 13:43 Grandmasterchoda Which one of you retards called this already?
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2022.01.24 13:43 ApexPredator1995 Hi. new GoW player here on PC. When do i get the slash blades?
Never played GoW but saw on YT. Im surprised i dont have the slash blades i saw in the previous games.
when do i get those?
im in the giant region with the huge claw.
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2022.01.24 13:43 Rabbiv Get $30 Paypal / Giftcard after spending $30 online (Bestbuy, Walmart, Amazon, Target...)💸💸💵
2022.01.24 13:43 dem0n0cracy Associations Between Glycemic Traits and Colorectal Cancer: A Mendelian Randomization Analysis - Our results support a causal effect of higher fasting insulin, but not glucose traits or type-2 diabetes, on increased colorectal cancer risk.
Associations Between Glycemic Traits and Colorectal Cancer: A Mendelian Randomization Analysis
Neil Murphy, PhD, Mingyang Song, MD ScD, Nikos Papadimitriou, PhD, Robert Carreras-Torres, PhD, Claudia Langenberg, MD PhD, Richard M Martin, PhD, Konstantinos K Tsilidis, PhD, Inês Barroso, PhD, Ji Chen, PhD, Tim Frayling, PhD ... Show more Author Notes
JNCI: Journal of the National Cancer Institute, djac011, https://doi.org/10.1093/jnci/djac011 Published: 20 January 2022
Glycemic traits—such as hyperinsulinemia, hyperglycemia, and type-2 diabetes—have been associated with higher colorectal cancer risk in observational studies; however, causality of these associations is uncertain. We used Mendelian randomization (MR) to estimate the causal effects of fasting insulin, 2-hour glucose, fasting glucose, glycated hemoglobin (HbA1c), and type-2 diabetes with colorectal cancer.
Genome-wide association study summary data were used to identify genetic variants associated with circulating levels of fasting insulin (n = 34), 2-hour glucose (n = 13), fasting glucose (n = 70), HbA1c (n = 221), and type-2 diabetes (n = 268). Using two-sample MR, we examined these variants in relation to colorectal cancer risk (48,214 cases and 64,159 controls).
In inverse-variance models, higher fasting insulin levels increased colorectal cancer risk (odds ratio [OR] per 1-standard deviation [SD]=1.65, 95% CI = 1.15–2.36). We found no evidence of any effect of 2-hour glucose (OR per 1-SD = 1.02, 95% CI = 0.86–1.21) or fasting glucose (OR per 1-SD = 1.04, 95% CI = 0.88–1.23) concentrations on colorectal cancer risk. Genetic liability to type-2 diabetes (OR per 1-unit increase in log odds = 1.04, 95% CI = 1.01–1.07) and higher HbA1c levels (OR per 1-SD = 1.09, 95% CI = 1.00–1.19) increased colorectal cancer risk, although these findings may have been biased by pleiotropy. Higher HbA1c concentrations increased rectal cancer risk in men (OR per 1-SD = 1.21, 95% CI = 1.05–1.40), but not in women.
Our results support a causal effect of higher fasting insulin, but not glucose traits or type-2 diabetes, on increased colorectal cancer risk. This suggests that pharmacological or lifestyle interventions that lower circulating insulin levels may be beneficial in preventing colorectal tumorigenesis. glycemic traits, insulin, glucose, type-2 diabetes colorectal cancer, Mendelian randomization
Topic: diabetes mellitus diabetes mellitus, type 2 colorectal cancer glucose fasting hemoglobin a, glycosylated fasting blood glucose measurement insulin mendelian randomization analysis Issue Section: Article
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2022.01.24 13:43 karenmaskin An elephant trying to stop a bulldozer from destroying its habitat
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2022.01.24 13:43 TomatoSea What's the quickest you ever left a job and why?
2022.01.24 13:43 Qlepto Pressing enter extends current block instead of adding new one?
For example, when I'm making a bullet list, normally pressing enter would create a new bullet but now when I press enter it just extends the current bullet point with no new bullet, can anyone help me change it back to default?
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2022.01.24 13:43 Huge-Scientist2640 How many schools look at current symester marks/transcript
I just sent my transcript for this previous symester (4th year fall term) and I was wondering how many schools will actually take those marks into account?
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2022.01.24 13:43 DJTheFirst Looking For Guidance
Hey everyone, im not exactly sure where to start here so forgive me if I bounce around.
I guess I should maybe start by telling about myself. Im 23, have a great start in my career path, have a gf, some hobbies. However im not really overly fond of myself, and im trying to learn to accept myself and grow.
ive always had an interest in meditation, and while through reading about it. I understand its not something that changes you as a person, now correct me if im wrong but its something you use for clarity. And im thinking that may be somewhere to start in my path.
Im really hoping for some tips or advice on how to start? I guess I practice breathing? And maybe think of something in particular? Please leave some comments and guidance. Or just anything.
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2022.01.24 13:43 Remote-Ad4701 HCG and penile growth
I have come across research that clearly proved that HCG extends penis when patient is sick on hypogonadism, but there is no study on regular, healthy people. My guess is that normal people who undergo same treatment, will see growth results.
Did any of u try to take HCG unblock for 8 weeks instead 3 and see any penile growth ?
Did anyone notice any growth after regular 3 weeks ?
Patients take 1500-2000 ui 3 times a week.
I am currently on same plan and will report results.
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2022.01.24 13:43 SaucerSwapTwitter Discord invites going out in a few hours! Remember to RETWEET the original Tweet 🔄 to engage the singularity 🌀🌀🌀 All that have retweeted will receive the invite today! 🛸👽🛸 $HBAR $FTM $SOL $SAUCE #DeFi https://t.co/bTOsTYNyUM
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